| Rank | Twitter Trend | Tweets Count |
|---|---|---|
| 1 | #wearamask | 154205 |
| 2 | #OverTheMoon | 141352 |
| 3 | #EricaNlewedim | 102950 |
| 4 | Sarah | 100791 |
| 5 | #tuesdaythoughts | 86066 |
| 6 | #TuesdayMotivation | 43115 |
| 7 | #ozomediatour | 42558 |
| 8 | Luton | 41472 |
| 9 | Greenwood | 36855 |
| 10 | Ratched | 30215 |
| 11 | Mason | 28454 |
| 12 | #MondayMotivation | 23535 |
| 13 | #CarabaoCup | 23412 |
| 14 | Henderson | 22884 |
| 15 | Lupe | 21051 |
| 16 | #worldrhinoday | 19980 |
| 17 | #HumanTrafficking | 19238 |
| 18 | Bailly | 17856 |
| 19 | lingard | 16830 |
| 20 | #23SeptemberCleanSA | 15700 |
| 21 | ighalo | 14045 |
| 22 | Van De Beek | 12267 |
| 23 | #NibasabaniAbelungu | 10959 |
| 24 | #nathanieljulies | <10k |
| 25 | #skeemsaam | <10k |
| 26 | #Dlozlami | <10k |
| 27 | Siba | <10k |
| 28 | #SouthAfricaRemix | <10k |
| 29 | ntsiki | <10k |
| 30 | #ChooseDay | <10k |
| 31 | #etvscandal | <10k |
| 32 | Pearl Thusi | <10k |
| 33 | Steers | <10k |
| 34 | #HeritageDay | <10k |
| 35 | Kwesta | <10k |
| 36 | #TheRiver1Magic | <10k |
| 37 | hilary swank | <10k |
| 38 | Felicity | <10k |
| 39 | #theinsidersa | <10k |
| 40 | #Gomora | <10k |
| 41 | #familyfeudafrica | <10k |
| 42 | #anewcultureofmoney | <10k |
| 43 | Mboro | <10k |
| 44 | #dataasseblief | <10k |
| 45 | #UthandoNoxolo | <10k |
| 46 | #TheQueenMzansi | <10k |
| 47 | #hungrylikealion | <10k |
| 48 | Nurkovic | <10k |
| 49 | #checkpoint | <10k |
| 50 | #LegacySA | <10k |